TFF2 and Anxiety: In the anxiety-like open field test, the BIG1 (post hoct(22) = 5.697, p < 0.0001), BIG2 (post hoct(22) = 5.008, p < 0.0001), C1 (post hoct(22) = 6.272, p < 0.0001), C2 (post hoct(22) = 5.927, p < 0.0001), and SML1 (post hoct(21) = 2.296, p < 0.032) OVX females spent significantly less time in the center when compared to the sham groups (F(1,134) = 119.24, p < 0.0001).