Significant levels were identified in EC-CFUs from benign breast disease patients treated with 10 pg/ml of TNF-α (n = 5, 1.875 ± 0.295, p = 0.0317) in comparison with those treated with 1 pg/ml (n = 5, 1.233 ± 0.0753). The gene discussed is TNF; the disease is breast fibrocystic disease.