VEGFA and age-related macular degeneration: The Minimally Classic/Occult Trial of the Anti-VEGF Antibody Ranibizumab in the Treatment of Neovascular Age-Related Macular Degeneration (MARINA) study demonstrated that 95% of ranibizumab-treated patients experienced visual improvement or stabilisation compared with 62% of sham-treated patients after 12 months [4].