IL10 and Alzheimer disease: IL-10 was also shown to be elevated in the injured adult brain in several neurodegenerative diseases and animal models of disease, such as excitotoxic shock [104], multiple sclerosis [105, 106], EAE [107–109], middle cerebral artery occlusion [110], traumatic brain injury [111], Alzheimer’s disease [112] and Parkinson’s disease [113].