TP53 and cancer: Kaplan-Meier survival curves (Figure 6) show that patients with TP53 mutations have significantly worse OS prognoses compared with those without TP53 mutations in seven cancer types: ACC, COAD, HNSC, KIRC, LAML, LUAD, and PAAD; however, they have better OS prognoses in GBM (log-rank test, unadjusted P-value < 0.05).