KEGG pathway analysis shows that these gene products are mostly involved in the cell cycle; the p53 signaling pathway; pathways in cancer and mismatch repair; and pathways that are specific for a number of different cancer types such as small-cell lung cancer, prostate cancer, bladder cancer, glioma, pancreatic cancer, melanoma, and chronic myeloid leukemia (FDR < 0.05; Supplementary Table S8). The gene discussed is TP53; the disease is central nervous system cancer.