LGR6 and Hand-foot syndrome: Eight weeks after the ablative dose, the skin was still perturbed with 2.0 (SEM 0.3) LacZ+ clusters of Lgr6 progeny per mm2 in the IFE versus 3.9 (SEM 0.6) in controls of which 52% (SEM 11%) versus 2.5% (SEM 0.4%) were associated with HFs.