To determine if MYC family proteins could cooperate with MCPyV IMR90 cells, we treated cells stably expressing ST, GFP, or p53DD + hTERT (PH) and MCPyV tumor-derived early-region (PHE) with inducible expression of MYC, MYCN or MYCL with dox for 48 hours and immunoblotted for HK2, MCT1 and LDHA (Fig 6B). The gene discussed is MYC; the disease is neoplasm.