We confirmed that FoxO1 and p27 were bona fide targets of miR-196a in NSCLC cells, by performing immunoblot analyses in BEAS-2B cells expressing miR-196a and in NCI-H460 cells in which the endogenous expression of miR-196a had been suppressed by use of anti-miR-196a (Figure 7C). The gene discussed is CDKN1B; the disease is non-small cell lung carcinoma.