PTEN and cancer: In this analysis, prognosis deteriorated continuously from 2,285 cancers without deletions to 1,324 cancers with 8p deletion only, to 400 cancers with PTEN deletion only, to 467 cancers with 8p/PTEN co-deletions (P = 0.0003 for PTEN deletion vs. 8p/PTEN co-deletion).