The NF-κB family of transcription factors, including p50, p52, RelA/p65, cRel and RelB, have been shown to play important roles in hippocampal neurogenesis and psychiatric disorders (Meffert et al., 2003; Crampton and O’Keeffe, 2013; Bortolotto et al., 2014; Aloor et al., 2015; Malki et al., 2015). Here, RELB is linked to psychiatric disorder.