We found that PARL and PINK1 could physically interacted, co-expressed and genetically interacted with those proteins of the reported leprosy susceptibility genes, such as OPA1, PARK2, HLA-A, HLA-DRA, HLA-DQB, and IL10RA (ref. 46 and references therein) (Figure S5). The gene discussed is HLA-A; the disease is leprosy.