Other nearby SNPs in high linkage disequilbrium (LD), have previously been reported for associations with BMI-adjusted adiponectin levels (rs6450176/rs4311394, r2=0.087, D′=0.87 (refs 37, 40)), high density lipoprotein C (HDL-C) levels (rs6450176 (refs 41, 42)) and risk of type 2 diabetes (rs702634, r2=1.0, D′=1.0 (ref. 38)). This evidence concerns the gene ADIPOQ and type 2 diabetes mellitus.