Two genes, actin-organizing protein KLHL1 at 13q21.33 and COL11A1 (collagen, type XI, alpha 1) at 1p21.1 were detected as joint deletions in all four cancer types (breast, ovarian, endometrial, and cervical, BOEC) (Fig. 4 and Additional file 14: Figure S5). This evidence concerns the gene KLHL1 and cancer.