For example, in breast cancer, we identified divide according to amplified or deleted regions genes TP53BP2, TP53INP1, K-RAS, BIRC5, TP53TG3, TP53I11, CCND1, FGFR1OP, ATM, PMS1, H-RAS, N-RAS, and MYCBP2. TP53BP2 gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. This evidence concerns the gene PMS1 and breast carcinoma.