In bivariate analysis (Table 2), baseline factors that predicted poor health outcome at 10 years of follow up included older age, male sex, black or Hispanic race/ethnicity (with white as reference group), smoking, presence of diabetes or hypertension, higher systolic and diastolic blood pressure, higher BMI, lower HDL cholesterol, higher coronary artery calcium score, higher CRP level, lower family income, lower educational attainment, occupation, and being unmarried. The gene discussed is CRP; the disease is diabetes mellitus.