CD8A and neoplasm: However, when irradiated 4T1 tumor cells were used to re-stimulate primed effector T cells, autologous DRibbles from 4T1 tumor cells and allo-DRibbles derived from C57MG tumor cells primed a similar level of 4T1 tumor-reactive CD8+ effector T cells (around 0.75% IFN-γ producing CD8+ T cells) (Fig. 2a, right panel).