The combined assay has recently also been used to screen patients with SCID [23, 24], ATM [12, 25], Wiskott-Aldrich syndrome (WAS) [26], DiGeorge syndrome [27–29], and trisomy 21 [30], and it has been suggested to be included in routine screening of newborns for primary immunodeficiency [31–34]. The gene discussed is ATM; the disease is Wiskott-Aldrich syndrome.