Among the patients with cirrhosis, there were 13 patients with reported drug-related adverse events (Table 4), the commonest of which (reported in more than 5% of patients) were increased ALT level (14.3%, 5/35), increased AST level (14.3%, 5/35), diarrhea (8.6%, 3/35), constipation (5.7%, 2/35), and malaise (5.7%, 2/35). The gene discussed is GPT; the disease is Cirrhosis.