After adjusting for district (Ilala, Kinondoni, and Temeke), calendar year and season of enrolment, age (<30, 30–39, 40–49, and ≥50 years), gender (male/female), BMI (underweight, normal weight, overweight, and obesity), CD4+ T-cell count (<350, 350–<500, and ≥500), WHO clinical disease stage (I, II, III, and IV), history of TB, and current TB/HIV coinfected, patients aged 40–49 years and those aged ≥50 years had a 43% [ARR 1.43 (95% CI 1.33, 1.53)] and 2-fold [ARR 2.52 (95% CI 1.92, 3.30)] increased risk for hypertension compared to patients aged 30–39 years. The gene discussed is CD4; the disease is hypertensive disorder.