RUNX1 and acute myeloid leukemia: Common targets for PCR-based MRD detection are fusion transcripts of mixed-lineage leukemia (MLL)-gene and CBF positive AML, e.g. runt-related transcription factor 1/runt–related transcription factor 1 translocated to 1 (RUNX1-RUNX1T1, formerly AML1-ETO) and core-binding factor subunit beta-myosin heavy chain 11 (CBFB-MYH11).