Serum levels of NO in AGD were lower 138.44 ± 19.20 μmol/L versus 190.57 ± 22.04 μmol/L in N-AGD (p = 0.042); antioxidant enzyme SOD activity was significantly diminished in AGD with 9.75 ± 0.52 U/mL versus 11.69 ± 0.55 U/mL in N-AGD (p = 0.012). Discussion. Patients with RT present with a similar state of the proinflammatory cytokines whether or not they have AGD. The gene discussed is SOD1; the disease is argyrophilic grain disease.