CFL1 and gastric cancer: After treatment with DDP for 24 h, the expression of p-cofilin-1 decreased significantly in BGC823 and SGC7901 cells, suggesting that DDP could induce p-cofilin-1 dephosphorylation and cofilin-1 activation in DDP-sensitive gastric cancer cell lines (Figures 4(b) and 4(c)).