Alopecia universalis, hyperthyrotropinemia, type I diabetes mellitus, dental enamel hypoplasia, developmental delay, short stature, candidiasis, hepatomegaly, multiple skeletal abnormalities, myopia, dysmorphic features, microcephaly, abnormal FAS-induced apoptosis. Hyper IgE. This evidence concerns the gene IGHE and Candidiasis, Invasive.