ANG and coronary artery disorder: In HFrEF group, plasma ANG levels were substantially higher compared with HFpEF group (393.6 (IQR [351.1,464.9]) versus 322.8 (IQR [262.7,417.2]) ng/mL, p < 0.001), while its levels in HFpEF group were higher than CHD disease controls significantly (322.8 (IQR [262.7,417.2]) versus 304.5 (IQR [254.0,370.5]) ng/mL, p < 0.001) (Figure 1(b)).