TRPV1 and Cerebral ischemia: To address this interaction between DEX, TRPM2 and TRPV1, we investigated the protective actions of DEX treatment on apoptosis, oxidative stress levels, Ca2+ entry values as well as involvement of TRPM2 and TRPV1 activations on the values in the DRG and HIPPO neurons in rat with cerebral ischemia.