HTR7 and cancer: MDA-MB-231 cancer cell-inoculated chick chorioallantoic membrane (CAM) assay was used to examine the in vivo efficacies of SB269970 (5-HT7 receptor inhibitor), wortmannin (an inhibitor of PI3K which is involved in the signaling of 5-HT7 and VEGF receptors), and BJ-1113.