In this study, we suggest BJ-1113 being considered as a potential anticancer agent that suppresses TNBC progression, by inhibiting both the Gαs-linked generation of cAMP and activation of the PI3K/Akt pathway (Fig. 8), and thus, suppressing invasion and proliferation of MDA-MB-231 cancer cells stimulated by 5-HT or serum. Here, AKT1 is linked to cancer.