A recent study of 299 type 2 diabetics and 500 unrelated normoglycemic subjects corroborated these findings in human sample by showing that T allele of single nucleotide polymorphism rs3743123 in GJD2 gene (coding for Cx36) leads to altered formation of gap junction plaques and cell coupling in β cells despite showing only marginal association to type 2 diabetes status [25]. Here, GJD2 is linked to type 2 diabetes mellitus.