For the XRCC1 Arg194Trp polymorphism, we found an increased likelihood of CAD susceptibility in recessive (TT vs. CT + CC: OR = 1.47, 95% CI = 1.13–1.93) and homozygous (TT vs. CC: OR = 1.37, 95% CI = 1.03–1.81) genetic models when cohorts from all eligible studies were pooled (Table 2; Fig 2). The gene discussed is XRCC1; the disease is coronary artery disorder.