IgAN patients had significantly higher levels of Gd-IgA1 compared to patients with other renal diseases(minimal change disease (MCD), membranous nephropathy, biopsy-proven nephro-arteriolosclerosis, Alport syndrome, thin basement nephropathy and mesangial proliferative glomerulonephritis) (P = 0.04, Heterogeneity: I2 = 93%). The gene discussed is IGHA1; the disease is lipoid nephrosis.