KDM4B and breast carcinoma: The interaction of KDM4B with MLL2 in breast cancer cells suggests that KDM4B may reinforce its associations with promoters by recruiting the deposition of H3K4me3.37 Although it is not yet known if MLL2 contributes to EOC, future studies examining the interactions between KDM4B, HIF, other KDMs and lysine methyltransferases will clarify the transcriptional mechanisms mediated by KDM4B in hypoxia and EOC.