Antiphospholipid syndrome (APS), both as a primary syndrome and as a syndrome secondary to systemic lupus erythematosus (SLE), is a systemic autoimmune disease defined by recurrent arterial/venous thromboembolic events and/or pregnancy morbidity in the presence of high titer antiphospholipid autoantibodies (aPL) in the plasma of patients [1, 2]. Here, FASLG is linked to antiphospholipid syndrome.