In the subgroups, the results showed evidence of significant association between Apo E gene polymorphism and CHD risk in the genetic model of E3/4 and E4/4 compared with the genotype E3/3 in eight Mongolian studies (E3/4 versus E3/3: OR = 1.73, 95% CI = 1.02–2.93; E4/4 versus E3/3: OR = 2.78, 95% CI = 1.35–5.72), while the variant genotypes ApoEE2/2, E2/3, and E2/4 were not associated with the increased risk of CHD (E2/2 versus E3/3: OR = 1.08, 95% CI = 0.39–3.00; E2/3 versus E3/3: OR = 1.16, 95% CI = 0.91–1.49; E2/4 versus E3/3: OR = 1.38, 95% CI = 0.62–3.11). This evidence concerns the gene APOE and coronary artery disorder.