NANOGP8 and posterior cortical atrophy: Here we address this critical question by performing genome-wide chromatin immunoprecipitation sequencing (ChIP-Seq) and transcriptome (that is, RNA sequencing (RNA-Seq)) analyses in LNCaP cells—a well-differentiated PCa cell line previously shown to harbor an androgen-independent (AI), self-renewing, stem-like cell subset [12]—modified to express a doxycycline (DOX)-inducible NANOGP8 transgene [9].