TLR4 and infection: We investigated whether infection of THP-1 macrophages by BCG-OtsB2 was associated with changes in cell-surface expression of a number of immune-related receptors including a number of receptors such as TLR2, TLR4, Mincle, Dectin-1 and CD-14 that have been implicated in phagocytosis of mycobacteria (Peterson et al., 1995; Ernst, 1998; Nicolle et al., 2004).