These include genes previously associated with diabetes (KLF7, MAN1A2),66,77 neurodevelopmental disorders (TC4F, NRXN1, AUTS2),69,73,74 autoimmune diseases (BSN),67 blood pressure (SAMD12, ZNF652)68,75 and cancer (ASXL3, AUTS2),76,74 although as yet not at a gold-standard genome-wide significance level. The gene discussed is ASXL3; the disease is cancer.