MEG3 and type 2 diabetes mellitus: Ten genes were uniquely expressed in beta cells, including MEG3, a type 1 diabetes (T1D)–associated lincRNA with reported expression in mouse beta cells and potential tumor suppressor activity (Modali et al. 2015), and IAPP, whose protein product, when aggregated, possesses cytotoxic properties that may contribute to beta cell death and dysfunction in T2D (Westermark et al. 2011).