ANLN NF was also an independent predictor of OS (HR = 1.61; 1.09–2.39, 95% CI, p = 0.018), BCSS (HR = 1.58; 1.05–2.38, 95% CI, p = 0.027) and RFS (HR = 1.67; 1.13–2.48, 95% CI, p = 0.010), when adjusted for Ki-67, tumor size, hormone receptor status, HER2 status, nodal status and age using multivariable cox regression models (Table 2). The gene discussed is ERBB2; the disease is neoplasm.