LOX and non-alcoholic fatty liver: We assessed similar metabolites in human liver and determined that the concentrations of 9‐ and 13‐HODE (which are regulated by LOX and derived from n‐6 fatty acid LA) were the most discriminating for NAFL and NASH, with both showing increases in NASH (Fig. 6C), whereas there was no difference in 15‐HETE concentration.