A possible mechanism to explain these reactions is that DINP, in combination with FITC, triggers the activation of NF-κB by ROS, which in turn promotes the production of TSLP and the activation of STAT3, STAT5 and STAT6, leading to the initiation of the sensitizing process and the exacerbation of allergic dermatitis. This evidence concerns the gene TSLP and atopic eczema.