FLT3 and acute myeloid leukemia: To assess the effect of NT1721 on the viability of various AML cell lines, we treated FLT3-ITD cells (Molm14, MV4.11) and FLT3-WT cells (THP1, KG1a) with increasing concentrations of NT1721 (0.1 nM - 10 μM) and determined the IC50 values after 48 h.