Heterogeneous nuclear ribonucleoprotein K was mainly expressed in the nuclei of the bladder cancer cells and was significantly overexpressed in bladder cancer tissues as compared with normal tissues (score: 143.3 ± 5.7 versus 95.3 ± 5.8, P < 0.001, Fig. 1B, Fig. S3). The gene discussed is HNRNPK; the disease is urinary bladder cancer.