Among these variants, four mapped to the 6q23 region, which is also associated with other autoimmune diseases including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), celiac disease (CeD), type 1 diabetes (T1D), inflammatory bowel disease (IBD), psoriasis (Ps) and psoriatic arthritis (PsA), and containing several candidate genes, such as TNFAIP3, AHI1 and IL22RA2 [7–13]. The gene discussed is IL22RA2; the disease is rheumatoid arthritis.