Additionally, the correlation analysis showed that the D-dimer level of the MCD-NS patients was positively correlated with the AKI stage and the serum creatinine, white blood cell, and interleukin-6 levels (r = 0.434, P =  < 0.001; r = 0.430, P =  < 0.001; r = 0.209, P = <0.001; and r = 0.340, P = <0.001, respectively). This evidence concerns the gene IL6 and acute kidney injury.