All multivariate analyses revealed that 18q deletion predicted PSA recurrence independently in all scenarios (P ≤ 0.0004) and that the predictive value of 18q deletion was largely independent of the ERG status (P ≤ 0.02 in ERG-negative and P ≤ 0.065 in ERG-positive cancers, Table 2). Here, KLK3 is linked to cancer.