HSF1 and HSPB1 inhibition increases the concentrations of iron and ROS in cells, ultimately suppressing the growth of tumour cells, whereas PKC‐regulated HSPB1 phosphorylation can prevent cell ferroptosis because phosphorylated HSPB1 inhibits the uptake of iron and lipid ROS by cells 65. The gene discussed is HSPB1; the disease is neoplasm.