SLC22A1 and type 2 diabetes mellitus: Our findings contrast to most of those previously reported in healthy subjects,15, 16, 17, 18 although it is in keeping with a recent study showing no impact of the OCT1 genotype on the glucose production in fasting healthy subjects.32 This may reflect the fact that our study was conducted on patients with T2D and, as such, we were able to assess HbA1c reduction rather than other surrogates of metformin response.