CRP and posterior cortical atrophy: As to PCa, elevated C-reactive protein value was a strong predictor of poor survival and lower probability of PSA response to treatment in patient with metastatic castration-resistant PCa who were receiving docetaxel-based therapy.[22] Besides, elevated NLR was closely associated with poor overall survival in patients with PCa.[5] Another study in Japan,[6] which was included 1464 patients, revealed that NLR was correlated with both cancer-specific survival (P = 0.018) and overall survival (P = 0.008) in patients with metastatic PCa.