Vimentin, S-100, CD68, and c-Kit have also been detected in some of the pigmented renal PEComa.[7,8] In our case, a panel of antibodies including: epithelial membrane antigen, cytokeratin antigens (AE1/AE3, CK7, CK18), mesenchymal antigens (SMA, vimentin, c-Kit, DOG-1), carcinoembryonic antigen (RCC antigen), neuroendocrine antigens (S-100, CgA, synaptophysin), adenoid antigen (CD-10), and HMB-45 were used to identify the immunoprofile of the tumor. The gene discussed is SYP; the disease is neoplasm.