Oxidative stress is also seen in glaucoma and other neurodegenerations (Chrysostomou et al., 2013; Inman et al., 2013; Burté et al., 2014; Kim et al., 2015; Yang et al., 2016) and reactive oxygen species such as peroxynitrate activate kinases including GSK-3β and p38 that modify tau and other proteins (Zhang et al., 2006). This evidence concerns the gene MAPT and glaucoma.