LEP and neoplasm: Tumor status induced a significant decrease in the expression of FIGF (P < 0.0001), ADIPOQ (P < 0.0001), LEP (P = 0.0009), PTHLH (P = 0.0345) and FOS-like Antigen 1 (FOSL1; P < 0.0001) compared with expression in corresponding non-tumor tissue (Fig. 5a).