GPRC5A is overexpressed in breast, colon and gastric cancers50, with the caveat that GPRC5A, among 80 genes, was significantly up-regulated in young BC patients (aged ≤45 years) relative to older, post-menopausal BCs (aged ≥65 years) (Fold change: 0.67; adjusted P < 0.01)11. The gene discussed is GPRC5A; the disease is breast cancer.