BBS10 and Bardet-Biedl syndrome: Similarly, recessive mutations in BBS10 (which encodes Bardet-Biedl syndrome 10)—mutations in which cause the rare Bardet-Biedl syndrome, a multisystemic disorder that also manifests truncal obesity [49]—have been found in individuals with morbid obesity and type 2 diabetes but no evidence of syndromic disease [50].